How can we judge whether breastcancer is axillary lymph node metastases. it will affect the survival of patients. Researchers from Harbin Medical UniversityCancer Hospital said, First screened 11 differential protein peaks. In clinical, diagnostic rate of breast cancer axillary lymph node metastasis as high as 83.3%. The latest study on breast cancer is part of a continuous update project run by the WCRF. Breast cancer is the most common cancer in women. Breast cancer is the leading cause of cancer deaths among women worldwide, according to the American Cancer Society. So many more die there with breast cancer than in the United States because early detection is the only thing we have - the closest thing we have to a cure. Whether the cancer axillary lymph node metastasis It is the most important factor in breast cancer. Generally believed that the number of lymph nodes affect the cure rate. Less than 1 cm in diameter Tiny breast cancer without lymph node invasion. 5-year survival rate can achieve up to 90%. The diameter of the tumor larger than 5 cm with lymph node metastasis, 5-year survival rate is only 40%. Results from this study will also allow them to determine whether Lymphatic Vascular Invasion can be incorporated into an improved prognostic index for early stage breast cancer. The researchers collected 66 female cases of venous blood samples, and then the serum was separated. Time mass spectrometry protein chip technology to obtain the original data, and then map out the protein mass spectra. after comparative analysis of axillary lymph node metastasis of serum protein fingerprint data, They found 11 differentially expressed protein peaks, Three protein peaks were selected And successfully build a model of two diagnostic classification. Detection rate of breast cancer axillary lymph node metastasis as high as 83.3%. The results show that serum protein fingerprinting can effectively distinguish between cases of breast cancer and non-breast cancer. Results from this study will also allow them to determine whether Lymphatic Vascular Invasion can be incorporated into an improved prognostic index for early stage breast cancer. the MVD of breast carcinoma was associated with tumor size (P<0.05), histologic grade (P<0.05), and axillary node status (P<0.05), but no association with estrogen receptor. Expression of MMP9 protein positively correlate with lymph node metastasis (P0.05).
